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BDBM43205 3-({[1-(1-Cyclopentyl-1H-tetrazol-5-yl)-2-methyl-propyl]-thiophen-2-ylmethyl-amino}-methyl)-8-methyl-1H-quinolin-2-one::3-[[[1-(1-cyclopentyl-1,2,3,4-tetrazol-5-yl)-2-methyl-propyl]-(thiophen-2-ylmethyl)amino]methyl]-8-methyl-1H-quinolin-2-one::3-[[[1-(1-cyclopentyl-5-tetrazolyl)-2-methylpropyl]-(thiophen-2-ylmethyl)amino]methyl]-8-methyl-1H-quinolin-2-one::3-[[[1-(1-cyclopentyltetrazol-5-yl)-2-methyl-propyl]-(2-thenyl)amino]methyl]-8-methyl-carbostyril::3-[[[1-(1-cyclopentyltetrazol-5-yl)-2-methylpropyl]-(thiophen-2-ylmethyl)amino]methyl]-8-methyl-1H-quinolin-2-one::MLS000031127::SMR000004539::cid_648964

SMILES: CC(C)C(N(Cc1cccs1)Cc1cc2cccc(C)c2[nH]c1=O)c1nnnn1C1CCCC1

InChI Key: InChIKey=RUSMMCWHLBQXAL-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 43205   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cell division cycle 42 (GTP binding protein, 25kDa)


(Homo sapiens (Human))
BDBM43205
PNG
(3-({[1-(1-Cyclopentyl-1H-tetrazol-5-yl)-2-methyl-p...)
Show SMILES CC(C)C(N(Cc1cccs1)Cc1cc2cccc(C)c2[nH]c1=O)c1nnnn1C1CCCC1
Show InChI InChI=1S/C26H32N6OS/c1-17(2)24(25-28-29-30-32(25)21-10-4-5-11-21)31(16-22-12-7-13-34-22)15-20-14-19-9-6-8-18(3)23(19)27-26(20)33/h6-9,12-14,17,21,24H,4-5,10-11,15-16H2,1-3H3,(H,27,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
PCBioAssay
n/an/an/an/a 1.63E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q22J698B
More data for this
Ligand-Target Pair