BDBM433461 US10562850, Compound 6d::US11066360, Compound 6d

SMILES CO[C@@H]1C[C@H](N(C1)C(=O)N(C)c1ccc(Cl)cc1)C(=O)Nc1cc(ccc1F)C(CCC1CC1)(N[S@](=O)C(C)(C)C)c1cccc(c1)C#N

InChI Key InChIKey=QHCSTFXYRQGZKO-PCMIATBVSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 433461   

TargetPlasma kallikrein(Homo sapiens (Human))
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM433461(US10562850, Compound 6d | US11066360, Compound 6d)
Affinity DataKi: >100nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates (DiaPharma Group, Inc., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM433461(US10562850, Compound 6d | US11066360, Compound 6d)
Affinity DataKi: >100nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates. In these experiments, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent