BDBM433508 US10562853, Compound 26

SMILES CNc1cccc(OCCNCC2(F)CCN(CC2)C(=O)c2ccc(F)c(Cl)c2)n1

InChI Key InChIKey=GPCOZCFGTRWRLE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 433508   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Neurolixis

US Patent
LigandPNGBDBM433508(US10562853, Compound 26)
Affinity DataKi:  0.0800nMAssay Description:5-HT1A: Radioligand binding was performed using membranes from CHO-K1 cells stably transfected with the human 5-HT1A receptor. All assays were carrie...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Neurolixis

US Patent
LigandPNGBDBM433508(US10562853, Compound 26)
Affinity DataKi:  320nMAssay Description:Alpha1-adrenergic Receptor: Radioligand binding was performed using tissue (rat cortex). All assays were carried out in duplicates. 50 μL workin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurolixis

US Patent
LigandPNGBDBM433508(US10562853, Compound 26)
Affinity DataKi:  850nMAssay Description:D2 Dopamine Receptor:Radioligand binding was performed using membranes from CHO-K1 cells stably transfected with the human D2 receptor. All assays we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent