BDBM43490 (E)-3-(4,6-dimethylpyrimidin-2-yl)sulfanyl-1-(4-fluorophenyl)prop-2-en-1-one::(E)-3-[(4,6-dimethyl-2-pyrimidinyl)thio]-1-(4-fluorophenyl)-2-propen-1-one::(E)-3-[(4,6-dimethylpyrimidin-2-yl)thio]-1-(4-fluorophenyl)prop-2-en-1-one::MLS000851117::SMR000457360::cid_5713207

SMILES Cc1cc(C)nc(S\C=C\C(=O)c2ccc(F)cc2)n1

InChI Key InChIKey=IIDUVXPAMLZRAI-BQYQJAHWSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 43490   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM43490((E)-3-(4,6-dimethylpyrimidin-2-yl)sulfanyl-1-(4-fl...)
Affinity DataEC50:  810nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM43490((E)-3-(4,6-dimethylpyrimidin-2-yl)sulfanyl-1-(4-fl...)
Affinity DataEC50:  1.24E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM43490((E)-3-(4,6-dimethylpyrimidin-2-yl)sulfanyl-1-(4-fl...)
Affinity DataEC50:  2.67E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay