BDBM4356 (2E)-2-cyano-N-(cyanomethyl)-3-(4-hydroxyphenyl)prop-2-enamide::benzylidenemalononitrile (BMN) deriv. 40

SMILES Oc1ccc(\C=C(/C#N)C(=O)NCC#N)cc1

InChI Key InChIKey=TWSUNDMWXLUVBD-JXMROGBWSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4356   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4356((2E)-2-cyano-N-(cyanomethyl)-3-(4-hydroxyphenyl)pr...)
Affinity DataKi:  3.60E+5nM IC50:  6.25E+5nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed