BDBM437447 4-ethoxy-1-methyl-5-(1-(1-(methylsulfonyl)piperidin-3- yl)-1H-pyrazol-4-yl)pyridin-2(1H)-one::US10617680, Example 181::US11020380, Example 181

SMILES CCOc1cc(=O)n(C)cc1-c1cnn(c1)C1CCCN(C1)S(C)(=O)=O

InChI Key InChIKey=PJBCVYYXVGJZMM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437447   

TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437447(4-ethoxy-1-methyl-5-(1-(1-(methylsulfonyl)piperidi...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437447(4-ethoxy-1-methyl-5-(1-(1-(methylsulfonyl)piperidi...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent