BDBM437649 2-cyclopropyl-6-(4-(6-methoxy-1'-methyl-6'-oxo-1',6'- dihydro-[3,4'-bipyridin]-3'-yl)-1H-pyrazol-1- yl)benzonitrile::US10617680, Example 383::US11020380, Example 383

SMILES COc1ccc(cn1)-c1cc(=O)n(C)cc1-c1cnn(c1)-c1cccc(C2CC2)c1C#N

InChI Key InChIKey=NMMUVOFNAMMIPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437649   

TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437649(2-cyclopropyl-6-(4-(6-methoxy-1'-methyl-6'-oxo-1',...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437649(2-cyclopropyl-6-(4-(6-methoxy-1'-methyl-6'-oxo-1',...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent