BDBM443224 N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)-5-(4-ethyl-4,7-diazaspiro[2.5]octan-7-yl)phenyl)acrylamide::US10654836, Example 5::US11001572, Example 5
SMILES CCN1CCN(CC11CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)c(NC(=O)C=C)c1
InChI Key InChIKey=XJVZSZODRVBVGV-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 443224
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 624nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 533nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 989nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 624nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 533nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 989nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair