BDBM445676 Ex. 14/KM-06-64/(I-14)::US10683309, Example 14::US11028104, Example 14
SMILES CCn1c2nc(Cc3cn4ccsc4n3)n(Cc3ccccc3)c2c(=O)[nH]c1=O
InChI Key InChIKey=PNOPLSUWJWBDPM-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 445676
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Affinity DataIC50: 68nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Affinity DataIC50: 11nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Affinity DataIC50: 68nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Affinity DataIC50: 11nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair