BDBM445682 Ex. 18/KM-06-99/(I-18)::US10683309, Example 18::US11028104, Example 18
SMILES CCn1c2nc(Cc3cn4CCCCc4n3)n(Cc3ccc(cc3)-c3ccn(C)n3)c2c(=O)[nH]c1=O
InChI Key InChIKey=OGPHSLXZCKRAAL-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 445682
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Affinity DataIC50: 209nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Affinity DataIC50: 30nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Affinity DataIC50: 209nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Affinity DataIC50: 30nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair