BDBM448223 US10689401, EX 25::US11008338, Example 25
SMILES CC(C)[C@H]1C[C@@H]2[C@](CO1)(NC(=N)C(C)(C)S2(=O)=O)c1ccccc1F
InChI Key InChIKey=OQFPZOUKNLLKGE-IIDMSEBBSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 448223
Affinity DataKi: 185nMAssay Description:BACE1: A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This a...More data for this Ligand-Target Pair
Affinity DataKi: 185nMAssay Description:BACE1: A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This a...More data for this Ligand-Target Pair
Affinity DataKi: 195nMAssay Description:BACE2: Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7...More data for this Ligand-Target Pair
Affinity DataKi: 195nMAssay Description:BACE-2: Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY...More data for this Ligand-Target Pair