BDBM448664 5-(tetrahydro-2H-pyran-4-yl)-N-(2-(4-(thiazol-4- ylmethyl)piperazin-1-yl)-5-(trifluoromethyl)phenyl)furan-2- carboxamide::US10696661, Compound 19

SMILES FC(F)(F)c1ccc(N2CCN(Cc3cscn3)CC2)c(NC(=O)c2ccc(o2)C2CCOCC2)c1

InChI Key InChIKey=BPHOSLIAHDYBRE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448664   

TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate

US Patent
LigandPNGBDBM448664(5-(tetrahydro-2H-pyran-4-yl)-N-(2-(4-(thiazol-4- y...)
Affinity DataIC50:  1.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent