BDBM448715 N-(2-(4-(isoxazol-5-ylmethyl)piperazin-1-yl)-5-(trifluoro- methyl)phenyl)picolinamide::US10696661, Compound 62

SMILES FC(F)(F)c1ccc(N2CCN(Cc3ccno3)CC2)c(NC(=O)c2ccccn2)c1

InChI Key InChIKey=GNDOCZPPCWSMGM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448715   

TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate

US Patent
LigandPNGBDBM448715(N-(2-(4-(isoxazol-5-ylmethyl)piperazin-1-yl)-5-(tr...)
Affinity DataIC50:  2.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent