BDBM4635 2-chloro-4-fluoro-5-{[6-methoxy-7-(2-methoxyethoxy)cinnolin-4-yl]amino}phenol::4-anilinocinnoline deriv. 18::CHEMBL150826::KDR Kinase Inhibitor, 6
SMILES COCCOc1cc2nncc(Nc3cc(O)c(Cl)cc3F)c2cc1OC
InChI Key InChIKey=JDPAKZCGVWMFFH-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 4635
Affinity DataIC50: 50nMpH: 7.4 T: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition assay using KDR.More data for this Ligand-Target Pair
Affinity DataIC50: >3.30E+4nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit FGFR-1 TK activity. The compounds were incubated with enzyme 20 min at room ...More data for this Ligand-Target Pair