BDBM4659 4-Anilinoquinazoline 6::N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-[2-(4-methylpiperazin-1-yl)ethoxy]quinazolin-4-amine
SMILES COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCN1CCN(C)CC1
InChI Key InChIKey=GSFNVLNOUTVLFC-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 4659
Affinity DataIC50: 300nMpH: 7.4 T: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit FGFR-1 TK activity. The compounds were incubated with enzyme 20 min at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair