BDBM466561 N-{2-[6-(Trifluoromethyl)-3′,6′-dihydro[2,4′-bipyridin]-1′ (2′H)-yl]ethyl}-tetrahydro-2H-pyran-3-carboxamide::US10800755, Example 16::US11014905, Example 16
SMILES FC(F)(F)c1cccc(n1)C1=CCN(CCNC(=O)C2CCCOC2)CC1
InChI Key InChIKey=LUQGVAHGIPCKGZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 466561
Affinity DataKi: 6nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Affinity DataKi: 1.69E+3nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sumitomo Dainippon Pharma
US Patent
Sumitomo Dainippon Pharma
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:The activity of the present compound for inhibiting hERG channel was measured by whole-cell patch clamp method with auto patch clamp system, using CH...More data for this Ligand-Target Pair
Affinity DataEC50: 31nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.69E+3nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Affinity DataEC50: 43nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair