BDBM475 (Hydroxyethyl)urea Isostere deriv. 3::benzyl N-[(1S)-2-carbamoyl-1-{[(2S,3R)-3-hydroxy-4-[(methylcarbamoyl)(2-methylpropyl)amino]-1-phenylbutan-2-yl]carbamoyl}ethyl]carbamate

SMILES CNC(=O)N(CC(C)C)C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1

InChI Key InChIKey=KGHZDRBKSVQHQS-KMDXXIMOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Washington University

Curated by ChEMBL
LigandPNGBDBM475((Hydroxyethyl)urea Isostere deriv. 3 | benzyl N-[(...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research

LigandPNGBDBM475((Hydroxyethyl)urea Isostere deriv. 3 | benzyl N-[(...)
Affinity DataIC50:  1.50E+3nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed