BDBM476998 Inhibitor 18 of SARS-CoV-2 Mpro

SMILES Fc1c(Cl)cc(cc1OCc1ccccc1Cl)-c1cc(cn(-c2cccnc2)c1=O)-c1c[nH]c(=O)[nH]c1=O

InChI Key InChIKey=FBYZCSUBKCAJAK-UHFFFAOYSA-N

Data  1 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 476998   

TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476998(Inhibitor 18 of SARS-CoV-2 Mpro)
Affinity DataIC50:  28nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476998(Inhibitor 18 of SARS-CoV-2 Mpro)
Affinity DataEC50:  1.00E+3nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM476998(Inhibitor 18 of SARS-CoV-2 Mpro)
Affinity DataEC50:  3.20E+3nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB