BDBM47880 1-(3-phenylpropyl)indole-2,3-dione::1-(3-phenylpropyl)isatin::MLS001183545::SMR000502001::cid_2282752

SMILES O=C1N(CCCc2ccccc2)c2ccccc2C1=O

InChI Key InChIKey=YDZPVQACTLRICO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 47880   

Target3C-like protease(Avian infectious bronchitis virus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM47880(1-(3-phenylpropyl)indole-2,3-dione | 1-(3-phenylpr...)
Affinity DataIC50:  1.85E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM47880(1-(3-phenylpropyl)indole-2,3-dione | 1-(3-phenylpr...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human ALDH1A1 using propionaldehyde as substrate preincubated for 2 mins followed by substrate addition by spectrophotometry in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM47880(1-(3-phenylpropyl)indole-2,3-dione | 1-(3-phenylpr...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human ALDH2 using propionaldehyde as substrate preincubated for 2 mins followed by substrate addition by spectrophotometry in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase, dimeric NADP-preferring(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM47880(1-(3-phenylpropyl)indole-2,3-dione | 1-(3-phenylpr...)
Affinity DataIC50:  460nMAssay Description:Inhibition of full length human ALDH3A1 expressed in Escherichia coli BL21 (DE3) using benzaldehyde as substrate preincubated for 2 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed