BDBM479476 ML300-based SC inhibitor 15::acs.jmedchem.1c00409_ST.288

SMILES O=C(Cn1nnc2ccccc12)N(Cc1ccsc1)c1ccc(cc1)-c1ccncc1

InChI Key InChIKey=ZFYLJRHNLKAHPV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 479476   

TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Cleveland Clinic

LigandPNGBDBM479476(ML300-based SC inhibitor 15 | acs.jmedchem.1c00409...)
Affinity DataIC50:  1.57E+3nMAssay Description:The protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, end point assay adapted from a previ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Cleveland Clinic

LigandPNGBDBM479476(ML300-based SC inhibitor 15 | acs.jmedchem.1c00409...)
Affinity DataIC50:  2.00E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Cleveland Clinic

LigandPNGBDBM479476(ML300-based SC inhibitor 15 | acs.jmedchem.1c00409...)
Affinity DataIC50:  2.09E+3nMAssay Description:The protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, end point assay adapted from a previ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed