BDBM479503 ML300-based SC inhibitor 42

SMILES Clc1cccc(CN(C(=O)Cc2cccnc2)c2ccc(cc2)-c2cn[nH]c2)c1

InChI Key InChIKey=LLFIKGDQQRLTFJ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 479503   

TargetReplicase polyprotein 1ab(2019-nCoV)
Cleveland Clinic

LigandPNGBDBM479503(ML300-based SC inhibitor 42)
Affinity DataIC50:  1.27E+3nMAssay Description:The protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, end point assay adapted from a previ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Cleveland Clinic

LigandPNGBDBM479503(ML300-based SC inhibitor 42)
Affinity DataIC50:  864nMAssay Description:The protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, end point assay adapted from a previ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB