BDBM48044 3-amino-4,6-dimethyl-N-piperonyl-thieno[2,3-b]pyridine-2-carboxamide::3-amino-N-(1,3-benzodioxol-5-ylmethyl)-4,6-dimethyl-2-thieno[2,3-b]pyridinecarboxamide::3-amino-N-(1,3-benzodioxol-5-ylmethyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide::3-azanyl-N-(1,3-benzodioxol-5-ylmethyl)-4,6-dimethyl-thieno[2,3-b]pyridine-2-carboxamide::VU0152099-1::cid_1541501

SMILES Cc1cc(C)c2c(N)c(sc2n1)C(=O)NCc1ccc2OCOc2c1

InChI Key InChIKey=AZOGCTMOKNTHIU-UHFFFAOYSA-N

Data  1 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 48044   

TargetMuscarinic acetylcholine receptor M4(RAT)
Vanderbilt Screening Center For Gpcrs, Ion Channels And Transporters

Curated by PubChem BioAssay
LigandPNGBDBM48044(3-amino-4,6-dimethyl-N-piperonyl-thieno[2,3-b]pyri...)
Affinity DataKi:  46.8nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of a Highly Selective in vitro and in vivo...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMuscarinic acetylcholine receptor M4(RAT)
Vanderbilt Screening Center For Gpcrs, Ion Channels And Transporters

Curated by PubChem BioAssay
LigandPNGBDBM48044(3-amino-4,6-dimethyl-N-piperonyl-thieno[2,3-b]pyri...)
Affinity DataEC50:  403nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of a Highly Selective in vitro and in vivo...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMuscarinic acetylcholine receptor M4(RAT)
Vanderbilt Screening Center For Gpcrs, Ion Channels And Transporters

Curated by PubChem BioAssay
LigandPNGBDBM48044(3-amino-4,6-dimethyl-N-piperonyl-thieno[2,3-b]pyri...)
Affinity DataEC50:  400nMAssay Description:Positive allosteric modulation of rat M4 AchRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(RAT)
Vanderbilt Screening Center For Gpcrs, Ion Channels And Transporters

Curated by PubChem BioAssay
LigandPNGBDBM48044(3-amino-4,6-dimethyl-N-piperonyl-thieno[2,3-b]pyri...)
Affinity DataEC50:  369nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of a Highly Selective in vitro and in vivo...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMuscarinic acetylcholine receptor M4(RAT)
Vanderbilt Screening Center For Gpcrs, Ion Channels And Transporters

Curated by PubChem BioAssay
LigandPNGBDBM48044(3-amino-4,6-dimethyl-N-piperonyl-thieno[2,3-b]pyri...)
Affinity DataEC50: <1.42E+3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of a Highly Selective in vitro and in vivo...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay