BDBM480755 N-(2,2-dimethyl-6-morpholino- 3H-benzofuran-5-yl)-5-oxo-4H- pyrazolo[1,5-a]pyrimidine-3- carboxamide::US10899774, Example 71::US11034698, Example 49

SMILES CC1(C)Cc2cc(NC(=O)c3cnn4ccc(=O)[nH]c34)c(cc2O1)N1CCOCC1

InChI Key InChIKey=OKKXBHWKOBOMGK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 480755   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM480755(N-(2,2-dimethyl-6-morpholino- 3H-benzofuran-5-yl)-...)
Affinity DataKi:  930nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM480755(N-(2,2-dimethyl-6-morpholino- 3H-benzofuran-5-yl)-...)
Affinity DataKi:  930nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent