BDBM483710 1-(4-(2-(pyrrolidin- 1-yl)-4- (trifluoromethyl)- benzyl)piperazine-1- carbonyl)-1H- pyrazole-3- carboxamide::US10927105, Ex 173::US11655217, Example 173

SMILES NC(=O)c1ccn(n1)C(=O)N1CCN(Cc2ccc(cc2N2CCCC2)C(F)(F)F)CC1

InChI Key InChIKey=BFVBUTIKSZEFAE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 483710   

TargetMonoglyceride lipase(Homo sapiens (Human))
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483710(1-(4-(2-(pyrrolidin- 1-yl)-4- (trifluoromethyl)- b...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM483710(1-(4-(2-(pyrrolidin- 1-yl)-4- (trifluoromethyl)- b...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483710(1-(4-(2-(pyrrolidin- 1-yl)-4- (trifluoromethyl)- b...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid 2-hydroxylase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483710(1-(4-(2-(pyrrolidin- 1-yl)-4- (trifluoromethyl)- b...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent