BDBM486281 US10947203, No. LC-82
SMILES COc1ccc(O)cc1-n1nnc(c1C)S(=O)(=O)c1ccc(c(O)c1)C(C)(C)C
InChI Key InChIKey=UNGPHIHVYYGYJO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 486281
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
St. Jude Children''S Rsearch Hospital
US Patent
St. Jude Children''S Rsearch Hospital
US Patent
Affinity DataIC50: 1.72E+4nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
St. Jude Children''S Rsearch Hospital
US Patent
St. Jude Children''S Rsearch Hospital
US Patent
Affinity DataIC50: 40nMAssay Description:The time-resolved fluorescence resonance transfer (TR-FRET) hPXR competitive binding assay was performed according to the manufacturer's instruct...More data for this Ligand-Target Pair