BDBM486281 US10947203, No. LC-82

SMILES COc1ccc(O)cc1-n1nnc(c1C)S(=O)(=O)c1ccc(c(O)c1)C(C)(C)C

InChI Key InChIKey=UNGPHIHVYYGYJO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 486281   

TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM486281(US10947203, No. LC-82)
Affinity DataIC50:  1.72E+4nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM486281(US10947203, No. LC-82)
Affinity DataIC50:  40nMAssay Description:The time-resolved fluorescence resonance transfer (TR-FRET) hPXR competitive binding assay was performed according to the manufacturer's instruct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent