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BDBM49032 6-amino-3-phenyl-4-propan-2-yl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::6-amino-4-isopropyl-3-phenyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::6-azanyl-3-phenyl-4-propan-2-yl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::MLS000054953::SMR000017376::cid_2881578

SMILES: CC(C)C1C(C#N)C(=N)Oc2[nH]nc(c12)-c1ccccc1

InChI Key: InChIKey=HXTBJLLOMVCAAN-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 49032   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(1A) dopamine receptor


(Homo sapiens (Human))
BDBM49032
PNG
(6-amino-3-phenyl-4-propan-2-yl-2,4-dihydropyrano[2...)
Show SMILES CC(C)C1C(C#N)C(=N)Oc2[nH]nc(c12)-c1ccccc1
Show InChI InChI=1S/C16H16N4O/c1-9(2)12-11(8-17)15(18)21-16-13(12)14(19-20-16)10-6-4-3-5-7-10/h3-7,9,11-12,18H,1-2H3,(H,19,20)
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PC cid
PC sid
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Similars

PCBioAssay
n/an/an/an/a 0.00658n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair