BDBM490760 US10968236, Compound I-88

SMILES OC1CO[C@]2(CCN(C2)c2ccc(Nc3cc(nc4CNC(=O)c34)-c3c(F)cccc3C#N)nc2)C1

InChI Key InChIKey=ABXUXWWAZGQYFE-XJCVEMOTSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 490760   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM490760(US10968236, Compound I-88)
Affinity DataKi: <10nMAssay Description:Tyk2 & JAK2: The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using micro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM490760(US10968236, Compound I-88)
Affinity DataKi: <10nMAssay Description:Tyk2 & JAK2: The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using micro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent