BDBM490794 US10968242, Example 19 Peak 3

SMILES Cn1cnc2n(cnc2c1=O)[C@@H]1C[C@@H]2OP(S)(=O)O[C@@H]3[C@@H](COP(S)(=O)O[C@@H]1[C@@H]2O)O[C@H]([C@H]3F)n1cnc2c1ncn(C)c2=O

InChI Key InChIKey=UPQZHDLOWBOXBM-ACVOEFHBSA-N

Data  1 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 490794   

TargetStimulator of interferon genes protein(Human)
Pfizer

US Patent
LigandPNGBDBM490794(US10968242, Example 19 Peak 3)
Affinity DataKi:  2nMAssay Description:A radioligand binding assay was developed to determine compound interactions were competitive with a tritium-labeled version of the native STING liga...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein [H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM490794(US10968242, Example 19 Peak 3)
Affinity DataKd:  2nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Pfizer

US Patent
LigandPNGBDBM490794(US10968242, Example 19 Peak 3)
Affinity DataKd:  3nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent