BDBM495051 US10995084, Ex. No. 2B-9

SMILES C[C@@H](NC(=O)c1ccc(Oc2cc(C)n[nH]c2=O)c(C)c1)C(=O)N1[C@@H](CC[C@@H]1C(C)(C)O)c1cccc(Cl)c1

InChI Key

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 495051   

TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM495051(US10995084, Ex. No. 2B-9)
Affinity DataKi:  0.0400nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM495051(US10995084, Ex. No. 2B-9)
Affinity DataIC50:  0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent