BDBM495289 CVD-0018773::MAT-POS-af1eef35-2

SMILES COC(=O)CN(C)S(=O)(=O)N1CC(C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc2C1

InChI Key InChIKey=GLLFHKJANJSNEG-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 495289   

TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM495289(CVD-0018773 | MAT-POS-af1eef35-2)
Affinity DataIC50:  115nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM495289(CVD-0018773 | MAT-POS-af1eef35-2)
Affinity DataIC50:  65nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PDB3D3D Structure (crystal)