BDBM496846 SARS-CoV-2 PLpro Inhibitor, 76
SMILES COC(=O)c1ccc(s1)-c1cccc(c1)[C@@H](C)NC(=O)c1cc(NC2CNC2)ccc1C
InChI Key InChIKey=CFQSYTCHYSNACR-MRXNPFEDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 496846
Affinity DataIC50: 810nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair
Affinity DataIC50: 810nMAssay Description:Inhibition of SARS-CoV-2 PLproMore data for this Ligand-Target Pair
Affinity DataKd: 2.40E+3nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 ug/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair