BDBM496854 SARS-CoV-2 PLpro Inhibitor, 84
SMILES C[C@@H](NC(=O)c1cc(NC2CNC2)ccc1C)c1cccc(c1)-c1ccc(CN2CC[C@H](O)C2)s1
InChI Key InChIKey=NDXWDWBHDSNJNP-DVECYGJZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 496854
Affinity DataIC50: 700nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of SARS-CoV-2 PLproMore data for this Ligand-Target Pair
Affinity DataKd: 668nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 ug/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair