BDBM497041 US11001561, Compound 34::US11702392, Compound 34

SMILES Cc1nc(N2C[C@H]3COC[C@@]3(CN)C2)c(C)c(=O)n1-c1cccc(Cl)c1Cl

InChI Key InChIKey=XGLLUQZUPXOKHO-ORAYPTAESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 497041   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Merck Patent

US Patent
LigandPNGBDBM497041(US11001561, Compound 34 | US11702392, Compound 34)
Affinity DataIC50:  1.70E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM497041(US11001561, Compound 34 | US11702392, Compound 34)
Affinity DataIC50:  1.70E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent