BDBM497048 US11001561, Compound 41::US11702392, Compound 42
SMILES Cc1nc(cc(=O)n1-c1cccc(Cl)c1Cl)N1CCC(CC1)NC[C@@H](O)CO
InChI Key InChIKey=VRIXJOTVGWDUKV-CQSZACIVSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 497048
Affinity DataIC50: 4.30E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair