BDBM497052 US11001561, Compound 45::US11702392, Compound 45

SMILES C[C@@H]1OCC2(CCN(CC2)c2nc(C)n(-c3ccc4ccccc4c3)c(=O)c2C)[C@@H]1N

InChI Key InChIKey=GSMKCWVXUQULKB-HTAPYJJXSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 497052   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Merck Patent

US Patent
LigandPNGBDBM497052(US11001561, Compound 45 | US11702392, Compound 45)
Affinity DataIC50:  1.20E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM497052(US11001561, Compound 45 | US11702392, Compound 45)
Affinity DataIC50:  1.20E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent