BDBM497077 US11001561, Compound 66a::US11702392, Compound 66a
SMILES Cc1nc(N2CCC3(Cc4ncccc4[C@H]3N)CC2)c(C)c(=O)n1-c1cccc(Cl)c1Cl
InChI Key InChIKey=PUAFKERZWLWHED-OAQYLSRUSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 497077
Affinity DataIC50: 73nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair