BDBM497123 US11001561, Compound 98::US11702392, Compound 98

SMILES COc1ccc(c(Cl)c1Cl)-n1c(C)nc(N2CCC3(CO[C@@H](C)[C@H]3N)CC2)c(C)c1=O

InChI Key InChIKey=XCKXUUJRVQSCDW-ORAYPTAESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 497123   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Merck Patent

US Patent
LigandPNGBDBM497123(US11001561, Compound 98 | US11702392, Compound 98)
Affinity DataIC50:  500nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM497123(US11001561, Compound 98 | US11702392, Compound 98)
Affinity DataIC50:  500nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent