BDBM497124 US11001561, Compound 99::US11702392, Compound 99

SMILES C[C@@H]1OCC2(CCN(CC2)c2nc(C)n(-c3ccc(F)c(Cl)c3Cl)c(=O)c2C)[C@@H]1N

InChI Key InChIKey=IXVLQWQFOCCZOG-KPZWWZAWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 497124   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Merck Patent

US Patent
LigandPNGBDBM497124(US11001561, Compound 99 | US11702392, Compound 99)
Affinity DataIC50:  28nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM497124(US11001561, Compound 99 | US11702392, Compound 99)
Affinity DataIC50:  28nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent