BDBM497143 US11001561, Compound 118::US11702392, Compound 118
SMILES N[C@@H]1c2ccccc2CC11CCN(CC1)c1cc(=O)n(c(N)n1)-c1cccc(Cl)c1Cl
InChI Key InChIKey=UJEVJWRWBCTRKW-OAQYLSRUSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 497143
Affinity DataIC50: 16nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair