BDBM497331 US11739077, Example 15::US11739077, Example 18::US11739077, Example 5

SMILES Cc1cc([nH]n1)-c1ccc(cc1)C(=O)[C@H]1CCCC[C@H]1C(=O)Nc1cn(C)nc1C#N

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 497331   

TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM497331(US11739077, Example 15 | US11739077, Example 18 | ...)
Affinity DataIC50: <50nMAssay Description:Human recombinant USP1/UAF1 expressed in baculovirus infected Sf21 cells were used (R&D, E-568-050). Test compound and/or vehicle was incubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM497331(US11739077, Example 15 | US11739077, Example 18 | ...)
Affinity DataIC50: <50nMAssay Description:Human recombinant USP1/UAF1 expressed in baculovirus infected Sf21 cells were used (R&D, E-568-050). Test compound and/or vehicle was incubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM497331(US11739077, Example 15 | US11739077, Example 18 | ...)
Affinity DataIC50: <50nMAssay Description:Human recombinant USP1/UAF1 expressed in baculovirus infected Sf21 cells were used (R&D, E-568-050). Test compound and/or vehicle was incubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent