BDBM497332 US11001595, Compound 4::US11111252, Compound 3

SMILES COc1ccc(Sc2sc3nc(N)nc(N)c3c2C)cc1

InChI Key InChIKey=ANAUCVSZRHVHHS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 497332   

TargetDihydrofolate reductase(Pneumocystis jirovecii)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM497332(US11001595, Compound 4 | US11111252, Compound 3)
Affinity DataIC50:  213nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM497332(US11001595, Compound 4 | US11111252, Compound 3)
Affinity DataIC50:  1.41E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM497332(US11001595, Compound 4 | US11111252, Compound 3)
Affinity DataIC50:  252nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University Of The Holy Spirit

US Patent
LigandPNGBDBM497332(US11001595, Compound 4 | US11111252, Compound 3)
Affinity DataIC50:  970nMAssay Description:Table 7: The inhibitory activities of TMP and TMQ are listed for comparison. While the tested compounds displayed reduced potency against pjDHFR comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent