BDBM497344 US11739077, Example 30::US11739077, Example 8

SMILES Cn1ncc(NC(=O)[C@H]2CCCC[C@@H]2C(=O)c2ccc(cc2)-c2cc[nH]n2)c1C#N

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 497344   

TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM497344(US11739077, Example 30 | US11739077, Example 8)
Affinity DataIC50: <50nMAssay Description:Human recombinant USP1/UAF1 expressed in baculovirus infected Sf21 cells were used (R&D, E-568-050). Test compound and/or vehicle was incubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM497344(US11739077, Example 30 | US11739077, Example 8)
Affinity DataIC50: <50nMAssay Description:Human recombinant USP1/UAF1 expressed in baculovirus infected Sf21 cells were used (R&D, E-568-050). Test compound and/or vehicle was incubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent