BDBM498129 US11013745, Compound E-Y45
SMILES Fc1ccc2OCCc2c1CNc1ncc(C2=CCN(CC2)C(=O)C=C)c2nncn12
InChI Key InChIKey=SMFXHNXJTMDNIG-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 498129
TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED [40-441]/Polycomb protein SUZ12(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataIC50: 3.40nMAssay Description:The TR-FRET method was used to measure the PRC2 enzyme activity. First, the enzyme was mixed with compounds at different concentrations and incubated...More data for this Ligand-Target Pair