BDBM498230 US11014911, Example 55

SMILES CC(C)NC(=O)O[C@@H]1CC[C@@H](C1)c1cc(NC(=O)Cc2ccc3n(C)ncc3c2)n[nH]1

InChI Key

Data  2 KI

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 498230   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM498230(US11014911, Example 55)
Show SMILES CC(C)NC(=O)O[C@@H]1CC[C@@H](C1)c1cc(NC(=O)Cc2ccc3n(C)ncc3c2)n[nH]1
Affinity DataKi:  0.100nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM498230(US11014911, Example 55)
Show SMILES CC(C)NC(=O)O[C@@H]1CC[C@@H](C1)c1cc(NC(=O)Cc2ccc3n(C)ncc3c2)n[nH]1
Affinity DataKi:  10.4nMAssay Description:The purpose of GSK3β assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid