BDBM498316 US11014911, Example 141

SMILES C[C@H]1CCCN1C(=O)O[C@@H]1CC[C@@H](C1)c1cc(NC(=O)Cc2cnc3ncnn3c2)n[nH]1

InChI Key

Data  2 KI

Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 498316   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM498316(US11014911, Example 141)
Show SMILES C[C@H]1CCCN1C(=O)O[C@@H]1CC[C@@H](C1)c1cc(NC(=O)Cc2cnc3ncnn3c2)n[nH]1
Affinity DataKi:  0.0800nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM498316(US11014911, Example 141)
Show SMILES C[C@H]1CCCN1C(=O)O[C@@H]1CC[C@@H](C1)c1cc(NC(=O)Cc2cnc3ncnn3c2)n[nH]1
Affinity DataKi:  5.75nMAssay Description:The purpose of GSK3β assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid