BDBM498897 (3S,4R)-1-(N~2~- cyclohexyl- N~2~,N~6~,N~6~- trimethyl-D-lysyl)-4- {[(3,4-difluoro- phenyl)carbonyl]amino}- N-(thiophen- 2-ylmethyl)piperidine- 3-carboxamide::US11014920, Compound 5::US11014920, Compound 6
SMILES CN(C)CCCC[C@@H](N(C)C1CCCCC1)C(=O)N1CC[C@@H](NC(=O)c2ccc(F)cc2)[C@H](C1)C(=O)NCc1cccs1
InChI Key InChIKey=ZDBTUCOXLMAXBH-FRXPANAUSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 498897
Affinity DataIC50: 98.3nMAssay Description:Factor XIIa activity determinations were made in 50 mM HEPES buffer containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair
Affinity DataIC50: 71.6nMAssay Description:Factor XIIa activity determinations were made in 50 mM HEPES buffer containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair