BDBM499068 US11014929, Example 106::US11542265, Example 106

SMILES CN1CCN(Cc2ccc(cc2)-c2n[nH]c3cnc(nc23)-c2c(F)ccc3CNCCc23)CC1

InChI Key InChIKey=WZAPOMVQEZCSGG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 499068   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM499068(US11014929, Example 106 | US11542265, Example 106)
Affinity DataKi: <50nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM499068(US11014929, Example 106 | US11542265, Example 106)
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent