BDBM499122 US11014930, Example 44
SMILES Nc1ncnc2n(nc(C(=O)Nc3cc(Br)[nH]n3)c12)C1CCC(F)(F)CC1
InChI Key InChIKey=NWQFFTMPQORXBA-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 499122
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Taiho Pharmaceutical
US Patent
Taiho Pharmaceutical
US Patent
Affinity DataIC50: 4.58nMAssay Description:To measure the inhibitory activity, first, the compounds of the present invention were individually diluted with dimethyl sulfoxide (DMSO) stepwise. ...More data for this Ligand-Target Pair