BDBM499179 US11014963, Example 73

SMILES COc1ccc(cc1)[C@H](NC(=O)[C@H](Cc1cccc(c1)C#N)NC(=O)c1cccc(OCC(=O)OC(C)(C)C)c1)C(=O)N[C@@H](C(C)C)C(=O)C(F)(F)F

InChI Key InChIKey=QNTDVVLNONBUSF-GOBOWQCMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 499179   

TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM499179(US11014963, Example 73)
Affinity DataIC50:  0.710nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent