BDBM499681 US11020397, Compound Formula-(II5)

SMILES CSc1nc(O)c(C(=O)Nc2ccc(cc2C#N)-c2c[nH]nn2)c(=O)[nH]1

InChI Key InChIKey=ZTGQWQGSBKBHPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 499681   

TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Acquist

US Patent
LigandPNGBDBM499681(US11020397, Compound Formula-(II5))
Affinity DataIC50:  0.0400nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Acquist

US Patent
LigandPNGBDBM499681(US11020397, Compound Formula-(II5))
Affinity DataIC50:  7.50E+3nMAssay Description:URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent